Welcome to the CoValence Labs Blog!

Information in our industry travels fast which is why we have created the CoValence Labs Blog. The purpose of our blog is to educate and discuss industry news with anyone and everyone that is involved with the personal care industry. We will be utilizing our blog as well as our Facebook and Twitter accounts to keep communication flowing, educating and to ultimately enhance our customer service.

The new communication avenues listed above will not replace our SKINsider and SKINsider FLASH E-newsletters. Please contact us if you would like to receive our SKINsiders available to all personal care professionals.


SKINsider – May 2010

5.5.10

May’s edition of Around the Water Cooler is targeting ‘out of the box’ ideas for preventing skin aging.

Step Away from the Bubble Gum (maybe)


Skin Inc. posted an article in March titled, “Could Gum-chewing Cause Wrinkles; Shorten Filler Lifespan?”. Based on beauty blogs, and not research, the article stated that there seems to be a gum-wrinkle connection due to the repetitive motion of chewing gum. However, on the flip-side, research has discovered that chewing gum can decrease stress and increases alertness. Hmm… is gum the culprit or repetition? According to Joel Schlessinger, MD, a board-certified dermatologist and cosmetic surgeon, “Repetition is the culprit.”

So, feel free to keep chewing gum to reduce stress… in moderation.

Stop – Drop – Relax

Have you felt stressed this last week? Last hour? According to www.motivationalplus.com some of the symptoms of a stressed woman are… guilt, weight gain, moody, anxiety, rushed, feeling overwhelmed and irritable. After some research, you also need to add… premature aging of skin. We (not our loved ones or co-workers) may be able to deal with the moodiness, but premature aging of the skin? No thank you!

An easy way to reduce stress is to – stop, drop and relax! We have found that spraying a room or work space with the Bio-Guard Mist (VLT0.6700) is an effective way to create a peaceful environment, reducing stress, even if the restful feeling only lasts a couple moments before someone needs you to save the world.

The Bio-Guard Mist is popular for promoting health (immune stimulating, antimicrobial, decongestant), wellness (stress relief, emotional balance, mental clarity, energizing) and environmental cleanliness. Therefore, to help promote beautiful, healthy skin… find and embrace an extra free moment in your day, spray Bio-Guard Mist and let the stress melt away. You are worth it!

Multi-Task Age Fighters

Enhancements in Cosmeceuticals makes it easier than ever to multi-task a skin care regimen and, concurrently, gives us more time to enjoy the rest of our day. We, at CoValence, are biased. We admit it. We love the products we make whether the products are custom or for our Vault. Each product has a story and a purpose, but we are especially fond of our products that fight age, not with one ingredient ‘jab’… but a ‘TKO’ combination of ingredients and benefits.

Here is a list of our Color Palette products which are perfect examples of multi-task age fighters…

  • Sweet Pea Pink Cheek Gel (VLT0.7501)
  • Bronze Glow Cheek Gel (VLT0.7502)
  • Rose is a Rose Cheek Gel (VLT0.7503)
  • Red Infusion Cheek Gel (VLT0.7504)
  • Volu-9 Lip Tint (VLT0.8000)
  • Hint of Tint Serum Anti-Age (Medium VLT0.4011, Light VLT0.4013)
  • Hint of Tint Serum Clarifying (Medium VLT0.4012, Light VLT0.4014)

SIRTUIN – A Knight in Shining Armor


An easy way for one to remember the benefits of a Sirtuin is to picture a Knight in Shining Armor – bravely protecting the DNA of our cells from destruction of aging scavengers.

Sirtuins are protein enzymes that affect cellular metabolism which plays a vital role in the manifestations of aging. Research is ongoing in this area, but there has been successful approaches conducted towards finding methods that fuel sirtuins. Research has shown that there are effective sirtuin activating compounds which promote the cell’s resistance to stress factors as well as prolong a cell’s life.

Resveratrol and its derivative compounds (Giant Knotweed), are some of the most compelling activators of sirtuins – lengthening a cell’s lifespan. According to Jin Liu, “combining the resveratrol amalgam with the various specified ingredients achieves significant effects such as the following: inhibits fatty acid oxidation and helps to keep cell membranes in good condition.” In addition, the sirtuin activators are capable of stimulating collagen and elastin plus inhibiting inflammation, tyrosinase activity and glycosylation processes – an infantry of anti-aging knights.

It would be our pleasure to customize a product for you with sirtuin activators. Not interested in customizing? Our emollient Night Cream (VLT0.5004) was created to help activate sirtuins.

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Good things come in small packages

4.22.10

CoValence is happy to announce that the following Vault products will be offered in a 16 oz. size in order for you to effectively test the products in your market, for a limited time (offer good until 10.31.10).

Peptide-99™ Serum (VLT0.4015X) brightens, helps to protect from UV damage, hydrates, builds collagen and firms skin due to a dynamic blend of eight (8) performance peptides totaling 99% of the entire formula.

Hint of Tint Serum – Anti-Age (VLT0.4013X, VLT0.4011X) moisturizes and reduces wrinkles for mature, aging skin while providing sheer coverage. (Available in Light and Medium pigments)

Hint of Tint Serum – Clarifying (VLT0.4014X, VLT0.4012X) contains anti-inflammatory and healing ingredients Tea Tree Oil, Burdock and Willowherb Extracts while also providing sheer coverage. (Available in Light and Medium pigments)

Cheek Gels provides potent antioxidants with Phycocyanin and Camu Camu Fruit Extract while adding a touch of color to your cheeks…colors include:

  • Sweet Pea Pink (VLT0.7501X)
  • Bronze Glow (VLT0.7502X)
  • Rose is a Rose (VLT0.7503X)
  • Red Infusion (VLT0.7504X)

Volu-9 Lip Tint (VLT0.8000X) hydrates, strengthens and adds volume to the lips with Volufiline ™ while adding a dash of color.

Lash and Brow Peptide Serum (VLT0.7500X) thickens, lengthens, conditions and darkens lashes and brows with Myristoyl Pentapeptide-17, Malus Domestica (Apple) Fruit Extract and Tricholastyl®.

CoValence Sales Executives and your Account Executive are standing by, ready to answer your questions. Don’t forget to visit our Products Page to view our catalog.

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Distribution…Putting the Pieces into Place

4.15.10

During my college days, the three most important words in retail were, “Location. Location. Location.” If you are new to selling skincare, is that your mantra today? Probably not. Odds are, the three most important words to you are, “Distribution. Distribution. Distribution.” What’s the difference between the two thoughts? The most obvious is that you do not need a brick and mortar location to be successful in skincare. Success comes from not only great product ideas, but one must strategically interlock different distribution channels in order to satisfy the purchasing personalities of today’s consumers.

Visualize your distribution channels as a puzzle. How does the puzzle look to you? Is there one lonely piece? Are there ten pieces not fitting together – website, on-line beauty store, brick & mortar, boutique, spa, etc.? We, CoValence, understand that you have a very difficult job – finding the best distribution pieces that fit your business plan. You can count on us to provide outstanding customer service and ingenious product ideas, in order for you to focus on expanding and successfully interlocking your perfect distribution puzzle.

Melinda Wochner
COO / VP of Marketing

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Green Tea’s heavy hitting active constituent, EGCG…

4.12.10

Green Tea (Camellia Sinensis) has been regarded as a promoter of good health when consumed internally. However, here at CoValence, we like to take advantage of its ability to promote good cellular health by applying it topically.

The primary active ingredient found in green tea is a compound called Epigallocatechin Gallate or EGCG. In its pure form, EGCG acts as a potent antioxidant which protects the skin from free-radical induced lipid peroxidation and DNA damage. Additionally, it stimulates our cell’s ability to produce energy and promotes wound healing by aiding in the differentiation of new skin cells. EGCG’s ability to protect as well as heal damaged skin makes it a priceless active in our skin care formulate.

Contact your Account Executive today to learn more about EGCG and how it can benefit your skincare products.

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SKINsider – March 2010

3.25.10


 

Color Palette Series


 It’s Spring — which makes it the perfect time to introduce our new Cosmeceutical make-up, highlighted in our Color-Palette series! If you did not receive our RSS last week, please take a moment to look at the Color-Palette blog.  We have introduced these Vault products at a special introductory price and quantity, for you to test with your clients. The Color-Pallete series, formulated with our Chiral-Color complex, has become one of our favorite  product groupings. It will probably be one of your favorites as well!  

 


March 2010 Ingredient Perspective



Not only have there been vast changes in the raw ingredient industry since we published our 2009 Corporate Report — it has accelerated! 

There are more mergers and acquisitions going on between ingredient manufacturers than last year. What happens when there is a new owner? They make changes. For a raw ingredient producer, that means dropping older ingredients where there is NO demand. Just as in the fashion industry – vendors drop old styles to bring in new.

Example: CoValence has used an Apple MMPI ingredient for nearly four years, yet the ingredient producers just told us last week they will no longer make this ingredient. What’s the reason for the discontinuation? Everyone wants Apple Stem Cells. End of story. We do not get a warning phase. We are simply told it is no longer available when we place an order.   

I will not go on and on as to every last ingredient horror story we have had to deal with as a manufacturer. I will say that from the early 1990’s to 2003 I can only recall one ingredient that we were not able to get, all of a sudden, and we could not find a replacement.  From 2004 up until present day I would say there have been around 30 or more ingredients that were suddenly discontinued. The reasons for the discontinuation are outlined in the earlier report.   

We, as the manufacturer, do our best to match or find a like ingredient to one that has been discontinued. Sometimes we are able to find a match, however many times we search without any success.   Unfortunately, the unsuccessful matches could be for an ingredient, exclusive to one raw manufacturer that gives a particular base feel or texture. Which means the product will not feel exactly how it did in its original state. Additionally, two raw ingredients can have the same INCI but feel very different. Raw suppliers have their own formulas for producing the raw ingredient just as we do on finished formulas. Scent is a particularly difficult issue for the same reason.

I want to add a second part involving use of natural preservatives. For years we have used Benzyl Alcohol instead of Parabens. Benzyl Alcohol works for many products as it slips in elegantly and does not disturb scent or texture. Similar to Parabens! However, Benzyl Alcohol does not provide a long shelf life which made sense with our earlier formulas considering they were not designed for a shelf-life over 12 months. Times and demands have changed, therefore we now formulate our products for a longer shelf-life (when the actives allow it).

During our formulation transition for a longer shelf life, global dominant EU regulations only allow for a low level of Benzyl Alcohol which means that other natural preservatives must be added to extend a shelf life.  Since the perfect natural option does not exist yet, the process of extending a shelf life while accepting client and global demands has been very difficult, especially since almost every natural option changes the scent, texture or color of a product. Even though there is still no natural “Paraben” preservative option that will extend a shelf life while also creating an elegant texture, we continue to work towards perfecting the combination of natural preservatives that are available. (See ‘Preservatives: Let’s Make A Deal’ below)

TO OUR CLIENTS:

I am asking you to understand that the skin care business has changed. It is not what it was 10 years ago, let alone 15-20 years ago! Sophisticated skin care, which was the domain of professional skin care, is now the domain of L’Oreal, Proctor & Gamble and other mass market brands. The raw ingredient manufacturers are in the driver’s seat! What was once a small industry of high performance, professional skin care, focused in the U.S. and filling the professional skin care shows, is now ruled by mass market. Look at the Olay®, Pro-X® ads on TV. The voiceover says “We have a ‘protocol’ with these products to give you results you don’t need to see a dermatologist for.” In addition, their magazine ads have about 10 doctors signing off to that fact that a dermatologist is not needed. Neutrogena is now going in the same marketing direction.     

The raw ingredient suppliers are rapidly changing, merging, and dropping ingredients to keep up with supplying larger quantities to the increasingly larger clientele that now want growth factors, brightening, peptides, everything that used to be the domain  of licensed professionals. They want to make larger batches of fewer products.  

WHAT NOW:

COVALENCE: We will notify you as soon as we know of a change and discuss alternatives. Believe me when I say we always try first to find an exact or close replacement. But, we also have to be careful that the replacement choice is sustainable, to the best of our knowledge.  It is not pleasant for either of us to be faced with change when we all have enough to deal with as business owners and managers!  But, these changes will continue to happen; therefore, wasting time and energy fighting it just detracts from everyone’s energy in getting on with the plan to deal with it. 

YOU: It will be a mistake for you to think it is possible to go back to the “old days” of a product being able to stay the same for years.  It will be imperative for you to develop a “Change Plan” going forward.  

This Change Plan should include:

(1). Educate your clients about the nature of these industry changes and the role of raw ingredient manufacturers.  Develop your own method of notifying clients on a change and refer them back to this information as to why if needed.   

(2). Larger batches of each SKU makes change costs easier to manage. You can continue to use up any product that is already packaged. You can add on a corrective hang-tag even, until the current packaging is used. Larger batches can help both sides absorb costs of a change.

(3). When a change needs to happen, CoValence will provide marketing information as to why the change had to happen and why the new option is better. 

This is the nature of skin care now and into the future. Like it or not, the speed of new ingredient roll-outs, the discontinuance of ingredients and competition from pro-mimic large players are all part of the landscape. The great news for you is that CoValence clients can still successfully compete because they can introduce new concepts faster than the large brands. Plus, we are continuing to work on our own ingredient Intellectual Property, which WE control, not ingredient vendors. Eventhough you must incorporate into your business plans the potential for rapid change, rest assured that we, your manufacturing partner, are doing everything in our power to make the inevitable change bearable.

All my best,

Linda

Preservatives: Let’s Make a Deal



People want to think that they could pick the preservative behind Door #1, Door #2 or Door #3 and it would easily replace Parabens.  That is completely NOT the case. Parabens were used for years as they slipped in un-noticed to ANY formula – they do not alter the smell,  texture  and they perfectly preserved.  Plus, let’s face it… they are cheap which is why the mass market still uses them. 

Unfortunately, there is nothing like Parabens whatsoever in the all-natural world yet.  Nothing.  The closest to it is Phenoxyethanol, which is considered safe by the CIR reports – the source that governs our industry. However, it does have limited use restrictions in the EU and the comments on Skin Deep apply to very, very strong doses – not to finished products.  As most everyone should know, strong doses of almost anything can irritate or burn the eyes (the Glycolic Acid MSDS states this), cause cancer (eating too much grilled meat or too much sun exposure),  irritate the lungs if breathed in (any powder), cause allergies (so does DL-Alpha Tocopherol which many companies use because it’s cheap), endocrine disruption,  neurotoxicity (but no one wants  to examine putting unnatural hormone replacement on the skin and what that does to disrupt the  body)!   If only there was a group that dared to attack the real enemies to health that individuals are faced with on a daily basis. 

There is no natural preservative out there can cover all bases like Parabens did.  They either are not strong enough for the shelf-life  needed for global distribution, make a product smell,  or change the texture,  on and on.  The perfect preservative that works just like Parabens—does not exist –yet. 

Certain websites will continue to disapprove of everything out there as that is their business.   However, savvy skin care professionals are right to keep tabs on these things and the  development of new options as the raw ingredient industry keeps developing them. But, they also need to keep perspective on the balance between the value of results-driven products like CoValence offers  and the time needed for the  evolvement of new and better preservative options. It has been the mandate of CoValence from the beginning, to not be stagnant or resist change,  as better options become available. As surprising as it may seem, there is not a perfect natural preservative hiding behind any door. However, CoValence is proficient at formulating with natural preservatives to achieve the longest shelf-life along with the most elegant texture possible. Times have changed and CoValence is embracing it!

Chirally Correct: Mother Nature’s Handy-Work



Most people are either right-handed, or left-handed. Right-handed people work better with their right hand. Left-handed people work better with their left hand. Very few people are ambidextrous, who can work equally well with their right or left hand.

Mother Nature is the same way…

Mother Nature produces most natural ingredients in their left-handed or right-handed form. Left-handed ingredients have their key elements arranged in a left-handed pattern (Levo, L; or Sinister, S), while right-handed ingredients are arranged in a right-handed geometry (Dextro, D; or Rectus, R). Technically, it is called chirality or asymmetry, and such ingredients are called chiral or asymmetric. Chiral or asymmetric ingredients rotate polarized natural light in either a clockwise or counterclockwise direction. Mother Nature prefers to produce left-handed ingredients. Natural amino acids, and human DNA itself, are all left-handed, for example. In general, such ingredients when produced by typical chemical synthesis tend to be a 50:50 mixture of both (D) and (L) molecules. Such mixtures are called racemic, or DL (50% of D-form + 50% of L-form = DL, or racemic); these do not rotate polarized natural light.

Just like people, these right-sided or left-sided natural ingredients perform uniquely in many cases. A left-handed ingredient can have greater skin wrinkles reduction benefit than a right-handed ingredient – Ascorbic Acid being a prime example. An (L) ingredient can be skin soothing, while the same ingredient in its D-form may cause skin irritation. If skin irritation property of D-form is greater than skin soothing property of L-form, then the DL-form may cause skin irritation overall. The use of pure 100% L-form in such cases is essential.

Natural ingredients included in a cosmetic product, that are either (L) or (D), may not absorb into skin at the same rate. If an (L) ingredient is absorbed more rapidly, then a 50:50 mixture of both (L) and (D) ingredient may have lesser skin beneficial affects compared to the use of 100% pure (L) ingredient in that product. If the ingredient has been made via synthesis in a pure (L) or (D) form, then both the natural and the synthetic would provide the same and equal biological properties. Synthetic ingredients are not bad, as long as they are nature-equivalent and have no undesirable chemical impurities.

CoValence utilizes the ingredients in their correct left (L) or right (D) handed biospatial form in all cosmetic formulations to provide optimal benefits.

CoValence has also developed a proprietary methodology to enhance the skin absorption of natural ingredients that have an undesirable handedness (chirally incorrect) form. You can only imagine what this technology can do when used for desirably handed (chirally correct) ingredients!

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The Vault – March 2010

3.16.10

Spring officially begins March 20th and we feel it is a perfect time to celebrate the season with our new Color Palette Series — formulated with our Chiral-Color Complex.  

CoValence’s Color Palette Series includes a wide array of cheek gels, tinted face serums and a lip tint. As an added benefit, we are including our tested and approved Lash & Brow Serum along with the Color Palette Series.

Cheek Gels Sweet Pea Pink VLT0.7501, Bronze Glow VLT0.7502, Rose is a Rose VLT0.7503 and Red Infusion VLT0.7504 - The Cheek Gels strengthen the skin in addition to improving moisture and hydration. Our product testers commented on how the beautiful, light tints made their complexions more vibrant, even if they never wear make-up!

 Tinted Serum Anti Age – Light VLT0.4013 and Medium VLT0.4011 - The Anti-Age Tinted Serums effectively strengthen and improve hydration, as well as increase elasticity and firmness while leaving a more flawless complexion. Our product testers quickly noticed the benefits of the Anti-Age Tinted Serum after just one application. The Tinted Serums work well with all leave-on ‘starter’ skin care products (serums, moisturizers, etc.). However, the Tinted Serums can also be worn without an additional serums and/or moisturizers.

Tinted Serum Clarifying – Light VLT0.4014 and Medium VLT0.4012 - The Clarifying Tinted Serums effectively strengthen and improve moisture, while effectively clarifying the skin. We understand that it is difficult to find a tinted face serum that truly helps to improve oily, acneic skin, but the Clarifying Tinted Serum did improve the skin of our product testers. The Tinted Serums work well with all leave-on ‘starter’ skin care products (serums, moisturizers, etc.). The Tinted Serums work well with all leave-on ‘starter’ skin care products (serums, moisturizers, etc.). However, the Tinted Serums can also be worn without an additional serums and/or moisturizers.

Volu-9 Lip Tint VLT0.8000 - Spring is the time to strengthen and  improve the hydration in your lips, after the harsh winter weather. As you are improving your lips texture, you may as well help plump up the lips  with Volufiline ™ and add a soft, berry tint. Our product testers found that a little of the Volu-9 Lip Tint goes a long way, therefore a ¼ oz. jar would be sufficient for a retail size.

Lash & Brow Serum VLT0.7500. The CoValence formulation, composing of three (3) pivotal anti-age ingredients, thickens, lengthens, conditions and darkens the lashes and brows, which result in a youthful appearance. The Lash & Brow Serum is a perfect addition to any skin care line-up.

For a limited time we are offering the Cheek Gels and Volu-9 Lip Tint in a 16 oz size!

Please contact us for minimums and pricing.

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CoValence ERP System Challenge: Discrete vs. Process Manufacturing

3.12.10

From the CoValence Laboratories Manufacturing Department

Less than two years ago CoValence implemented a new ERP system that converted a discrete manufacturing database into a system designed specifically for the process manufacturer.  A discrete ERP system is designed to assemble “parts” to create a unit of 1 each.  However, we essentially sell formulas, which are a mixed relationship of ingredients that are brought together with a process.  We then fill our formulations into multiple types of finished goods.   Because the old system wasn’t able to fluidly work with our formulas and bill of materials, many side databases in applications such as Word and Excel had to be maintained in order for us to function in our day to day operations.  While the implementation of the new software was painful and at times appeared to be creating more work than it was saving, we can now “discretely” define the improvements to our company’s operating procedures.

The structure of our old system was inflexible and unforgiving, while the new system gives CoValence more control to comfortably define our manufacturing processes accurately.  We have perfected our weights to gallons, so now when a filling batch is created, we know exactly how much bulk product is needed for that Sales Order to be made.  It saves on time calculating each item that needs to be filled which is also more accurate than our employees doing it on a calculator and making a mistake.  Also, the new system shows exactly what ingredients or parts we are running low or critical on, whereas the old system didn’t show us this information at all. 

For the Marketing Department, immediate benefits were not straightforwardly seen, as the out-of-the-box software was tailored to the manufacturing side.  One of our most intensive projects when we initially went live was the INCI Customization created specifically for CoValence.  Historically, when a product was approved for production, the Marketing Department had to create INCI listings manually, which took about 30-40 minutes to create and at 5-20 listings a week, this was an average of 30 hours collectively for this department.  The INCI reports are a favorite of the Account Executives, because it saves so much time.  Prior to this they had to manually create our INCI listings using an Excel Spreadsheet to look up the ingredient and the corresponding INCI name and other information.  Now when a formula is approved, they can just run a report.

Our Shipping Department’s daily processes have also seen improvement with another adaptation created just for them, the Back Order Customization.  Our Shipping Clerks just run a report and the day’s backorders are printed which are then handed back to the Manufacturing Department.  Prior to this they had to look at the day’s shipping records manually, and reprint each order one by one.  Maintaining orders is a bit more intensive but from an inventory standpoint it is much clearer what is shipping, so mistakes are down to a minimum.

CoValence as a company is ingrained with a work culture that promotes it’s employees to always strive to improve our processes and overcome any limitations presented by our day to day operations – the ERP implementation and continued exploration of the potentials within our new software is an example of this dedication to delivering the best products and services possible.

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Ingredient Corner – DHA

3.4.10

Natural Self-Tanning is Here….

Dihydroxyacetone (DHA) is a naturally occurring substance found in plant and animals cells. When applied to the skin, DHA reacts with peptides and amino acids in the horny layer to generate a brown polymer called melanoidin. Groups of these melanoidins produce a safe, natural looking tan without the need for damaging sun or UV exposure.

Here at CoValence, we use a 100% all-natural DHA that is produced using a Gluten and GMO-free fermentation process. Our safe and eco-friendly self-tanning products can give your skin that sun kissed look, sans the skin damage. Speak to your Account Executive today about formulating with all-natural DHA.

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SKINsider – February 2010

2.25.10

Sharpen the Saw

Most of you have probably heard of the term “Sharpen the Saw” from the 7 Habits of Highly Effective People (Stephen R. Covey). If the term is new to you, it is stating that we must always keep improving. If we do not have time to sharpen our saws, because we are too busy sawing trees, we will never be able to do a good job. How many trees have you cut down with a dull saw? When was the last time you sharpened your saw?

CoValence will help you sharpen your saws. We provide industry, ingredient and CoValence information through our weekly blogs and monthly SKINsider. We are also working on a new 2010 initiative which will put more ingredient selling points and industry trends into your hands to help you sell your products!

In addition to receiving our blogs and SKINsider, you can link to more industry magazines on our website. Here are a few excellent resources that we find to be excellent resources:

 2010 is the time to step away from the trees and start sharpening your saw! CoValence is here to help!

Phycocyanin: A Novel Cosmetic Ingredient from Algae

Algae are photosynthetic organisms with a total of 2,530,000 species. Algae can be found with a diversity of forms and sizes, that can exist from unicellular microscopic organisms (microalgae) to multicellular of great size (macroalgae). Blue-green algae, also known as Cyanobacteria, are a very interesting natural source of new compounds with biological activity that could be successfully used as functional cosmetic ingredients. Blue-green algae are present in almost all aquatic ecosystems, including creeks, rivers, lakes and wetlands. It is the Phycocyanin Photosynthetic Pigment that gives Cyanobacteria their bluish color and the name “blue-green algae”. The antioxidant, anti-cancer, anti-inflammatory, neuroprotective, antimicrobial and radical scavenging activities of Phycocyanin from different Cyanobacteria are well documented, but they are rarely utilized.

Many adverse skin symptoms are accompanied or even caused by oxidative stress that is characterized by excessive formation of Reactive Oxygen Species (ROS) that cannot be counteracted by the antioxidant defense systems of the human body. Therefore the therapeutic application of natural Phycocyanin with strong antioxidant activity will be more useful to keep the skin healthy and young. Among the antioxidative agents Phycocyanin appears to be promising. It exerts also anti-inflammatory, neuroprotective and hepatoprotective effects, which are closely connected with its antioxidative activity.

Antioxidative Properties of Phycocyanin Demonstrated by In Vitro Studies

Lipid peroxidation mediated by ROS is believed to be an important cause of destruction and damage to cell membranes, because a simple initiating event can result in the conversion of hundreds of fatty acids side chain into lipid peroxides, which alters the structural integrity and biochemical functions of membranes, which causes premature aging symptoms and wrinkles. Dr. Remirez and coworkers from Ozone Research Center, Cuba showed that Phycocyanin significantly inhibits the increase in lipid peroxides and protect the cell membrane damage. The researchers from McGill University, Canada (Jensen et al. 2001) found that the whole Cyanobacteria are suggested to stimulate the human immune system and possess antioxidant, antimicrobial, anti-inflammatory, anti-viral, anti-cancer, cholesterol- lowering effects and human cells growth enhancement mainly because of their Phycocyanin content in the cell.

We are always interested at CoValence in exploring the potential natural green ingredients in our cosmetic products knowing that if we have the best ingredients, so will our clients. The Phycocyanin pigment from the blue-green algae is a recent addition to our green cosmetic ingredient list.

Around the Water Cooler

Here are some quick summaries from important articles that we have recently read. You may find them interesting topics to discuss around the water cooler or in your next company meeting.

American Trends: The Year Ahead (by Andrea Nagel; from WWD Special Report Issue 01.29.10)

A key strategy in 2010 is toward “increased brand diversity” and “companies shifting their category focus.”

(*) How can CoValence help you with this strategy? We have over 3000 professional, OTC and retail skincare/personal care formulas that can be quickly blended to fit all of your strategies. Our clients sell in the professional market, high end department stores, beauty specialty stores, infomercials, on-line, etc. We can quickly help you switch gears if you want to try your hand at different distribution channels.

Injectable Procedures Up in 2009 (from Skin Inc.; posted 02.01.10)

Facial “injectable procedures appear to have experienced a boost during the 4th quarter of 2009.”

(*) Do you have a product that is marketed as a complement to a facial injection procedure? If not, consider adding a new skincare product into your line up or simply ask CoValence to help you enhance any of your current products. A post-injection skincare product is a perfect opportunity to increase sales since injection procedures are increasing and individuals want to improve upon the injection results – thus getting more mileage out of the procedure.

2010 CoValence Innovations

As most of you know, CoValence has been manufacturing unique ingredient concept products since 1989.  Including the introduction of the concept of Chirality in skincare manufacturing, in the mid-90’s.  We are very interested in sophisticated, “mechanism of action” ingredients.  So, it is our pleasure to give you a glimpse of some of what we are working on for 2010:

  • MitoprotectTM 2: CoValence Laboratories developed the MitoprotectTM technology with encapsulated ingredients to nourish and stimulate the mitochondrial support enzymes.  Mitoprotect™ 2 will be introduced soon. 
  •  Plant Stem Cell (new – not on the market) technology for enhanced function of human stem cells via plant stem cell active components. 
  • Enhanced Spin Trap technology  formulated as a superior anti-ROS/DNA protective complex
  • Endothelin Antagonists for high efficiency skin lightening in human skin
  • Enhanced Sirtuin complexes


Natural Fragrance

Fragrances are typically composed of synthetic chemical isolates, essential oils and other aroma compounds. Some of those chemical isolates used by the fragrance industry were synthesized to cut costs, but were originally inspired by ones found in nature, i.e. Eugenol; which is found in clove, cinnamon and bay essential oils

A natural fragrance uses chemical isolates extracted directly from a natural, botanical source, thus eliminating the presence of synthetically derived chemicals and solvents. The main benefit of using this method is that the finished blend is considered natural. However, an additional benefit is that the perfumer has the ability to create a dramatically more complex and richer blend without the restrictions associated with blending solely with essential oils. 

What’s OLD is now NEW

 
CoValence started selling our Anti-A.G.E. complex back in the 1990’s. The Anti-A.G.E. complex was designed to fight against “Advanced Glycation End-products”. Yet, why is there an article in BlogBeyondBeauty.com titled “Glycation, the new word in the anti-age fight“? Our struggle with the article (new product introduction) is not with the idea of fighting glycation… we simply question the term “new magic word“. Maybe the title should have been, “Don’t forget about Glycation“! 

You may be wondering how CoValence could customize a product for you with an Anti-A.G.E. complex? Simple. An Anti-A.G.E. complex typically slips into most products without changing the texture, scent or color. Contact your Account Executive if you would like to enhance your products with an Anti-A.G.E complex of your own.

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Sneak Peak at Our New “Color Palette” Cosmeceuticals

2.17.10

Spring is a season of renewed color and beauty, which makes it the perfect time to introduce our new Color Palette series. CoValence’s Color Palette series includes a wide array of Tinted Cheek Gels, Tinted Face Serums and Volu-9 Lip Tint . The series also includes our tested and approved anti-age Lash & Brow Serum. More detailed information about the Color Palette series will be posted in March, when Spring officially begins!

 

In the meantime – When was the last time you took a look at the Products Page on our website? If it has been more than a month, you may have missed a new entry, or two. New products are added monthly!

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