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	<title>CoValence Laboratories: Private Label and Custom Skincare / Personal Care Manufacturer &#187; Argireline</title>
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		<title>Ingredient Corner &#8211; BOTOX® Alternatives</title>
		<link>http://www.covalence.com/news-wire/ingredient-corner-botox-alternatives/</link>
		<comments>http://www.covalence.com/news-wire/ingredient-corner-botox-alternatives/#comments</comments>
		<pubDate>Thu, 03 Sep 2009 19:57:46 +0000</pubDate>
		<dc:creator>Lauren</dc:creator>
				<category><![CDATA[Ingredient Corner]]></category>
		<category><![CDATA[anti-age]]></category>
		<category><![CDATA[Argireline]]></category>
		<category><![CDATA[botox]]></category>
		<category><![CDATA[Leuphasyl]]></category>
		<category><![CDATA[peptide]]></category>
		<category><![CDATA[Peptide 99 Serum]]></category>
		<category><![CDATA[Private Stock Peptide Serum]]></category>
		<category><![CDATA[Snap-8]]></category>

		<guid isPermaLink="false">http://www.covalence.com/?p=645</guid>
		<description><![CDATA[There are so many peptides and botanicals that claim to relax expression muscles reducing wrinkles that it is hard to tell them apart. We take a look at three of the heavy-hitter peptides in this competitive arena: Argireline®, Leuphasyl®, and SNAP-8.]]></description>
			<content:encoded><![CDATA[<p>A place where we highlight interesting ingredients to keep you In-The-Know.</p>
<p><strong>BOTOX® Alternatives</strong></p>
<p>Argireline® was the first peptide that claimed to be an alternative to Botulinum Toxin, and took the industry by storm. Now there are so many peptides and botanicals that claim to relax expression muscles reducing wrinkles that it is hard to tell them apart.  Let’s take a look at three of the heavy-hitter peptides in this competitive arena.</p>
<p>Argireline® is a hexapeptide that is a mimic of the N-terminal end of SNAP-25 which competes with the SNARE complex, stopping neurotransmitters from releasing and relaxing muscle contractions. Studies have confirmed a 32% decrease in deep wrinkles within 28 days when 5% is used twice daily. Years later, Lipotec decided to make a great thing even better, and along came Leuphasyl®. It is a pentapeptide that works synergistically with Argireline® for even better results. Leuphasyl® mimics the natural path of enkephalins coupling with enkephalin receptors to release G protein subunits which keeps neurons in their resting state, halting muscle contractions. The powerful combination of 5% Leuphasyl® and 5% Argireline® showed a maximum reduction in wrinkle depth of up to 47% over 28 days. Can peptides have children? Argireline® did. SNAP-8 is the elongation of Argireline® making it an octapeptide. It is a new analogue of the N-terminal end of SNAP-25, blocking the SNARE complex. Get this – studies have shown when 10% was applied twice a day for 28 days, there was a reduction of wrinkles of up to 63%! That is in time for that high school reunion.</p>
<p>Do they work as well as injected Botulinum Toxin? No, they do not. But they are an alternative for those wary of the needle or for the fearless, to prolong and enhance the effects of Botulinum Toxin.</p>
<p>Ask today how you can incorporate BOTOX® alternatives into your next development project.</p>
<p>Argireline®, Leuphasyl®, and SNAP-8 can be found in the Vault’s <strong>Peptide-99™ Serum (VLT0.4015G)</strong>. Argireline® is also in the <strong>Private Stock Peptide Serum (VLT0.4007G)</strong>. Contact your Account Executive for more information on BOTOX® alternatives and the Peptide-99™ and Private Stock Peptide Serums.</p>
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		<title>The Vault &#8211; April 09</title>
		<link>http://www.covalence.com/news-wire/the-vault-april09/</link>
		<comments>http://www.covalence.com/news-wire/the-vault-april09/#comments</comments>
		<pubDate>Tue, 21 Apr 2009 22:06:18 +0000</pubDate>
		<dc:creator>Lauren</dc:creator>
				<category><![CDATA[Vault]]></category>
		<category><![CDATA[antioxidant]]></category>
		<category><![CDATA[Argireline]]></category>
		<category><![CDATA[collagen]]></category>
		<category><![CDATA[epidermal growth]]></category>
		<category><![CDATA[hyaluronic acid]]></category>
		<category><![CDATA[Matrixyl 3000]]></category>
		<category><![CDATA[retinol]]></category>
		<category><![CDATA[serum]]></category>
		<category><![CDATA[vitamin c]]></category>
		<category><![CDATA[white tea]]></category>

		<guid isPermaLink="false">http://www.covalence.com/?p=171</guid>
		<description><![CDATA[Check out the new serums out in time for Spring.]]></description>
			<content:encoded><![CDATA[<p>The Vault is a growing selection of private label formulas from CoValence available for bulk purchase.</p>
<h1><strong>Spring Serums</strong></h1>
<p class="MsoNormal">We are excited to introduce a new variety of serums to The Vault.   The following serums are available during the month of May with a low minimum order of 1 gallon and a 10% discount.  Samples are available upon request.</p>
<p class="MsoNormal"><span> </span></p>
<p class="MsoNormal"><span><strong><span>Triple C Serum</span></strong><span> (SKU#VLT0.4006G) is a brilliant combination of three types of Vitamin C for optimal brightening, collagen synthesis and antioxidants benefits. </span></span></p>
<p class="MsoNormal"><strong><span>Vita A Serum</span></strong><span> (SKU# VLT0.4003G) is a smoothing retinol serum that promotes new tissue growth combat wrinkles and fine lines. </span></p>
<p class="MsoNormal"><span><strong><span>Vita A Alternative Serum</span></strong><span> (SKU# VLT0.4004G) is a gentle retinol free serum that provides the benefits of retinol.  Contains a special complex that increase the production of collagen, hyaluronic acid and epidermal growth factors. </span></span></p>
<p class="MsoNormal"><strong><span>Private Stock Peptide Serum</span></strong><span> (SKU# VLT0.4007G) is the ultimate peptide serum.  It contains the maximum recommended amount of Argireline™ and Matrixyl 3000™ with added anti inflammatory and antioxidant benefits of white tea. </span></p>
]]></content:encoded>
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